Transposable elements and xenobiotic resistance

Transposable elements or TEs are well known drivers of adaptive change in plants and animals but their role insecticide resistance remains poorly documented. This review examines the potential transposons identifies key areas where our understanding unclear. Despite well-known model systems such as upregulation Drosophila Cyp6g1 , many putative examples lack functional validation. The types transposon-associated changes that could lead to reviewed, including up-regulation, message stability, loss function alternative splicing. Where mechanisms appear absent from literature drawn other biology. Finally, ways suggested which transgenic expression be used validate biological significance TE insertion. In absence studies association genes therefore remain correlations.